Casey Gardner and Izzie both go to the same school. This is where them two meet. When they first meet, Izzie is shown to be rude to Casey. They later get on really well while in detention. However, Izzie pushes Casey away, because of an incident with Nate (Izzie's boyfriend). Later is Season 2, Izzie goes up to Casey's room (on Casey's 16th birthday). Izzie wants to be friends again and says "Lets forehead promise, to never leave eachother again." They put their foreheads together and lean in for a kiss. But, they are interrupted by Casey's mother (Elsa Gardner). In the last episode of Season 2, Casey and Izzie meet up and are sitting in Casey's car. The two hold hands, while sitting there silently.